INTRODUCTION

ZELGOR 250MG TABLET contains Abiraterone which belongs to a group of medicines called Androgen biosynthesis inhibitors. ZELGOR 250MG TABLET is used with prednisone/prednisolone in adult men to treat prostate cancer that has spread to other parts of the body.

ZELGOR 250MG TABLET is also to treat early stage of prostate cancer when used with androgen deprivation therapy (treatment that lowers testosterone hormone) and prednisone/prednisolone (medication) in affected individuals.

ZELGOR 250MG TABLET is not recommended for use in patients allergic to abiraterone. It is also not recommended for use in patients suffering from severe liver disease.

Before taking ZELGOR 250MG TABLET, inform your doctor if you have high blood pressure, any other blood vessel problems (such as blood pressure, stroke), swelling in the feet/ankles/legs, diabetes, lung problems (such as shortness of breath), heart problems (such as heart failure, irregular/rapid heart rate), kidney, and/or liver problems.

ZELGOR 250MG TABLET is not recommended for use in pregnant and breastfeeding women since it is intended to be used only in male patients.

ZELGOR 250MG TABLET is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 75 years/above) after consulting the doctor.

The most common side effects of taking ZELGOR 250MG TABLET are swelling in legs/feet, high blood pressure, urinary tract infection, diarrhea, indigestion, chest pain, irregular heartbeat, and/or rash. Contact your doctor if any of the symptoms worsen.

USES OF ZELGOR 250MG TABLET

With prednisone/prednisolone:

• Treats prostate cancer that has spread to other parts of the body
• Treats early stage of prostate cancer when used with androgen deprivation therapy (treatment that lowers testosterone hormone) in affected individuals

HOW ZELGOR 250MG TABLET WORKS

ZELGOR 250MG TABLET is an androgen biosynthesis inhibitor which works by inhibiting the production of 17α-hydroxylase (CYP17) enzyme needed to produce testosterone (male sex hormone) which enables the growth of cancer cells in the prostate gland. Since ZELGOR 250MG TABLET suppresses the production of testosterone, the cancer cells in the prostate gland won’t be able to grow thus preventing its effects on the gland in affected individuals.

DIRECTIONS FOR USE

Take ZELGOR 250MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Avoid taking the medicine with food. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF ZELGOR 250MG TABLET

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.

Indigestion:

Try to reduce consumption of tea, coffee, cola or alcohol and lose weight if you are obsese. Avoid smoking and do not eat three to four hours before going to bed. Consult your doctor if the symptom gets worse.

Rashes:

Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Consult and inform your doctor if the symptom gets worse.