Epzicom (Abamun L) 600 mg/300 mg Tablet
Epzicom (Abamun L) 600 mg/300 mg Tablet is a combination of two antiretrovirals. It is to treat HIV (human immunodeficiency virus) infection. It increases the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
- Category : HIV
- Manufacturer : Generic
- Active Substance : Abamun L
- Customer Rate
- Prescription : Required or Will Provide upon Online Doctor Consultation
INTRODUCTION
ABAMUNE L is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the treatment of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections.
Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections.
ABAMUNE L cannot not cure HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During treatment with ABAMUNE L your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects.
Do not take ABAMUNE L if you are allergic to abacavir or lamivudine. Before taking ABAMUNE L inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABAMUNE L to treat hepatitis B or C infection, do not stop taking it without consulting your doctor.
Even if you take ABAMUNE L, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABAMUNE L is not recommended for use in pregnant or breastfeeding women.
The most common side effects of taking ABAMUNE L are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABAMUNE L.
USES OF ABAMUNE L
- Treats HIV infection in adults, adolescents and in children (weighing above 25 kgs)
HOW ABAMUNE L WORKS
ABAMUNE L is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections.
DIRECTIONS FOR USE
Take ABAMUNE L as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABAMUNE L can be taken with or without meals.
Your doctor will decide the correct dose and for how long ABAMUNE L must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABAMUNE L without consulting your doctor as it may reduce its effectiveness.
SIDE EFFECTS OF ABAMUNE L
COMMON
- Difficulty in sleeping
- Feeling depressed
- Headache, tiredness, dizziness
- Nausea, diarrhoea
- Fever, skin rash
- Stomach pain
- Loss of appetite
- Irritated or runny nose
- Hair loss
UNCOMMON
- Decrease in RBC, WBC, and platelets
RARE
Stop taking ABAMUNE L and contact your doctor immediately if you experience any of the following side effects:
- Signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet)
- Pure red cell aplasia (failure of bone marrow to produce new red blood cells)
- Signs of infections (such as fever, headache, stomach-ache, breathing difficulty)
- Signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness)
- Signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving)
- Signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach)
- Heart attack
- Changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Nausea and Vomiting:
Take ABAMUNE L with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
WARNING & PRECAUTIONS
PREGNANCY
ABAMUNE L is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
BREASTFEEDING
Breastfeeding should be discontinued in mothers infected with HIV infection. However, consult your doctor before taking ABAMUNE L if you wish to breastfeed.
DRIVING AND USING MACHINES
Do not drive or operate any machines if your ability is affected by ABAMUNE L.
ALCOHOL
Avoid consumption of alcohol while taking ABAMUNE L.
KIDNEY
ABAMUNE L should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
LIVER
ABAMUNE L should be used with caution in patients with moderate to severe liver diseases (such as Hepatitis B or C). Therefore, consult your doctor before taking it.
ALLERGY
Do not take ABAMUNE L if you are allergic to abacavir or lamivudine.
HEART DISEASE
ABAMUNE L should be used with caution in patients with heart problems (such as high blood pressure). Therefore, consult your doctor before taking it.
OTHERS
ABAMUNE L is not recommended for use if you:
- Have a genetic problem (called as HLA-B*5701 allele)
Before taking ABAMUNE L inform your doctor if you:
- Are overweight
- Have diabetes
- Have high blood cholesterol levels
- Smoke
Use in pediatrics:
ABAMUNE L should be used with caution in children weighing above 25kg if prescribed by a physician. It is not recommended for use in children weighing less than 25kg. Therefore, consult your doctor before taking it.
Use in geriatrics:
ABAMUNE L should be used with caution in elderly people. Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug Interaction:
Before taking ABAMUNE L inform your doctor if you are taking any of the following medicines such as:
- Emtricitabine (another medicine used to treat HIV infection)
- Other antiviral combinations containing lamivudine (such as tenofovir/lamivudine, lamivudine/stavudine)
- Co-trimoxazole (trimethoprim/sulfamethoxazole) used to treat bacterial infections
- Cladribine (an anti-cancer medicine used to treat hairy cell leukaemia)
- Phenytoin (a medicine used to treat epilepsy)
- Methadone (a medicine used for pain relief)
- Medicines containing sorbitol and other sugar alcohols such as xylitol, mannitol, lactitol or maltitol
- Riociguat (a medicine used to treat increased pressure in the lungs)
Overdosage:
If you or anyone else accidentally took more ABAMUNE L, consult your doctor immediately.
SYNOPSIS
| Drug | : | Abacavir, Lamivudine |
| Pharmacological Category | : | Anti-Retroviral drugs |
| Therapeutic Indication | : | HIV infection |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep ABAMUNE L out of reach of children
- Store ABAMUNE L at room temperature
Epzicom (Abamun L) 600 mg/300 mg Tablet is a combination of two antiretrovirals. It is to treat HIV (human immunodeficiency virus) infection. It increases the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
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